diff --git a/tools/valgrind-webrtc/drmemory/suppressions.txt b/tools/valgrind-webrtc/drmemory/suppressions.txt
index 90831d1a9..49e86a215 100644
--- a/tools/valgrind-webrtc/drmemory/suppressions.txt
+++ b/tools/valgrind-webrtc/drmemory/suppressions.txt
@@ -939,3 +939,154 @@ name=https://code.google.com/p/webrtc/issues/detail?id=3490 (4)
 *!testing::internal::EqHelper<>::Compare<>
 *!rtc::AsyncWriteTest_TestWrite_Test::TestBody
 *!testing::internal::HandleSehExceptionsInMethodIfSupported<>
+
+UNINITIALIZED READ
+name=https://code.google.com/p/webrtc/issues/detail?id=3789 (1)
+drmemorylib.dll!replace_memcmp
+*!cricket::VideoFrame::Validate
+*!cricket::WebRtcVideoFrame::Reset
+*!cricket::WebRtcVideoFrame::Init
+*!VideoFrameTest<>::ConstructI4201Pixel
+*!WebRtcVideoFrameTest_ConstructI4201Pixel_Test::TestBody
+*!testing::internal::HandleSehExceptionsInMethodIfSupported<>
+
+UNINITIALIZED READ
+name=https://code.google.com/p/webrtc/issues/detail?id=3789 (2)
+*!cricket::VideoFrame::Validate
+*!cricket::WebRtcVideoFrame::Reset
+*!cricket::WebRtcVideoFrame::Init
+*!VideoFrameTest<>::ConstructI4201Pixel
+*!WebRtcVideoFrameTest_ConstructI4201Pixel_Test::TestBody
+*!testing::internal::HandleSehExceptionsInMethodIfSupported<>
+
+UNINITIALIZED READ
+name=https://code.google.com/p/webrtc/issues/detail?id=3789 (3)
+drmemorylib.dll!replace_memcmp
+*!cricket::VideoFrame::Validate
+*!VideoFrameTest<>::ValidateFrame
+*!VideoFrameTest<>::ValidateI420LargeSize
+*!WebRtcVideoFrameTest_ValidateI420LargeSize_Test::TestBody
+*!testing::internal::HandleSehExceptionsInMethodIfSupported<>
+
+UNINITIALIZED READ
+name=https://code.google.com/p/webrtc/issues/detail?id=3789 (4)
+drmemorylib.dll!replace_memcmp
+*!cricket::VideoFrame::Validate
+*!cricket::WebRtcVideoFrame::Reset
+*!cricket::WebRtcVideoFrame::Init
+*!VideoFrameTest<>::CopyToBuffer1Pixel
+*!WebRtcVideoFrameTest_CopyToBuffer1Pixel_Test::TestBody
+*!testing::internal::HandleSehExceptionsInMethodIfSupported<>
+
+UNINITIALIZED READ
+name=https://code.google.com/p/webrtc/issues/detail?id=3789 (5)
+*!cricket::VideoFrame::Validate
+*!cricket::WebRtcVideoFrame::Reset
+*!cricket::WebRtcVideoFrame::Init
+*!VideoFrameTest<>::CopyToBuffer1Pixel
+*!WebRtcVideoFrameTest_CopyToBuffer1Pixel_Test::TestBody
+*!testing::internal::HandleSehExceptionsInMethodIfSupported<>
+
+UNINITIALIZED READ
+name=https://code.google.com/p/webrtc/issues/detail?id=3789 (6)
+drmemorylib.dll!replace_memcmp
+*!cricket::VideoFrame::Validate
+*!cricket::WebRtcVideoFrame::Reset
+*!cricket::WebRtcVideoFrame::Init
+*!WebRtcVideoFrameTest::TestInit
+*!WebRtcVideoFrameTest_InitEvenSize_Test::TestBody
+*!testing::internal::HandleSehExceptionsInMethodIfSupported<>
+
+UNINITIALIZED READ
+name=https://code.google.com/p/webrtc/issues/detail?id=3789 (7)
+MSVCR120D.dll!mbctombb_l
+MSVCR120D.dll!vsnprintf_c_l
+MSVCR120D.dll!vsprintf_s_l
+MSVCR120D.dll!sprintf_s
+MSVCP120D.dll!std::num_put<>::do_put
+MSVCP120D.dll!std::num_put<>::put
+MSVCP120D.dll!std::basic_ostream<>::operator<<
+*!cricket::VideoFrame::Validate
+*!cricket::WebRtcVideoFrame::Reset
+*!cricket::WebRtcVideoFrame::Init
+*!WebRtcVideoFrameTest::TestInit
+*!WebRtcVideoFrameTest_InitEvenSize_Test::TestBody
+*!testing::internal::HandleSehExceptionsInMethodIfSupported<>
+
+UNINITIALIZED READ
+name=https://code.google.com/p/webrtc/issues/detail?id=3789 (8)
+drmemorylib.dll!replace_memcmp
+*!cricket::VideoFrame::Validate
+*!cricket::WebRtcVideoFrame::Reset
+*!cricket::WebRtcVideoFrame::Init
+*!WebRtcVideoFrameTest::TestInit
+*!WebRtcVideoFrameTest_InitOddWidth_Test::TestBody
+*!testing::internal::HandleSehExceptionsInMethodIfSupported<>
+
+UNINITIALIZED READ
+name=https://code.google.com/p/webrtc/issues/detail?id=3789 (9)
+MSVCR120D.dll!mbctombb_l
+MSVCR120D.dll!vsnprintf_c_l
+MSVCR120D.dll!vsprintf_s_l
+MSVCR120D.dll!sprintf_s
+MSVCP120D.dll!std::num_put<>::do_put
+MSVCP120D.dll!std::num_put<>::put
+MSVCP120D.dll!std::basic_ostream<>::operator<<
+*!cricket::VideoFrame::Validate
+*!cricket::WebRtcVideoFrame::Reset
+*!cricket::WebRtcVideoFrame::Init
+*!WebRtcVideoFrameTest::TestInit
+*!WebRtcVideoFrameTest_InitOddWidth_Test::TestBody
+*!testing::internal::HandleSehExceptionsInMethodIfSupported<>
+
+UNINITIALIZED READ
+name=https://code.google.com/p/webrtc/issues/detail?id=3789 (10)
+drmemorylib.dll!replace_memcmp
+*!cricket::VideoFrame::Validate
+*!cricket::WebRtcVideoFrame::Reset
+*!cricket::WebRtcVideoFrame::Init
+*!WebRtcVideoFrameTest::TestInit
+*!WebRtcVideoFrameTest_InitOddHeight_Test::TestBody
+*!testing::internal::HandleSehExceptionsInMethodIfSupported<>
+
+UNINITIALIZED READ
+name=https://code.google.com/p/webrtc/issues/detail?id=3789 (11)
+MSVCR120D.dll!mbctombb_l
+MSVCR120D.dll!vsnprintf_c_l
+MSVCR120D.dll!vsprintf_s_l
+MSVCR120D.dll!sprintf_s
+MSVCP120D.dll!std::num_put<>::do_put
+MSVCP120D.dll!std::num_put<>::put
+MSVCP120D.dll!std::basic_ostream<>::operator<<
+*!cricket::VideoFrame::Validate
+*!cricket::WebRtcVideoFrame::Reset
+*!cricket::WebRtcVideoFrame::Init
+*!WebRtcVideoFrameTest::TestInit
+*!WebRtcVideoFrameTest_InitOddHeight_Test::TestBody
+*!testing::internal::HandleSehExceptionsInMethodIfSupported<>
+
+UNINITIALIZED READ
+name=https://code.google.com/p/webrtc/issues/detail?id=3789 (12)
+drmemorylib.dll!replace_memcmp
+*!cricket::VideoFrame::Validate
+*!cricket::WebRtcVideoFrame::Reset
+*!cricket::WebRtcVideoFrame::Init
+*!WebRtcVideoFrameTest::TestInit
+*!WebRtcVideoFrameTest_InitOddWidthHeight_Test::TestBody
+*!testing::internal::HandleSehExceptionsInMethodIfSupported<>
+
+UNINITIALIZED READ
+name=https://code.google.com/p/webrtc/issues/detail?id=3789 (13)
+MSVCR120D.dll!mbctombb_l
+MSVCR120D.dll!vsnprintf_c_l
+MSVCR120D.dll!vsprintf_s_l
+MSVCR120D.dll!sprintf_s
+MSVCP120D.dll!std::num_put<>::do_put
+MSVCP120D.dll!std::num_put<>::put
+MSVCP120D.dll!std::basic_ostream<>::operator<<
+*!cricket::VideoFrame::Validate
+*!cricket::WebRtcVideoFrame::Reset
+*!cricket::WebRtcVideoFrame::Init
+*!WebRtcVideoFrameTest::TestInit
+*!WebRtcVideoFrameTest_InitOddWidthHeight_Test::TestBody
+*!testing::internal::HandleSehExceptionsInMethodIfSupported<>
diff --git a/tools/valgrind-webrtc/memcheck/suppressions.txt b/tools/valgrind-webrtc/memcheck/suppressions.txt
index 9381fae8e..40cb583aa 100644
--- a/tools/valgrind-webrtc/memcheck/suppressions.txt
+++ b/tools/valgrind-webrtc/memcheck/suppressions.txt
@@ -712,3 +712,67 @@
    fun:_ZN12_GLOBAL__N_118StatsCollectorTest22TestCertificateReportsERKN3rtc18FakeSSLCertificateERKSt6vectorISsSaISsEES4_S9_
    fun:_ZN12_GLOBAL__N_156StatsCollectorTest_ChainedCertificateReportsCreated_Test8TestBodyEv
 }
+{
+   bug_3789_1
+   Memcheck:Uninitialized
+   fun:_ZN7cricket10VideoFrame8ValidateEjiiPKhm
+   fun:_ZN7cricket16WebRtcVideoFrame5ResetEjiiiiPhmmmlli
+   fun:_ZN7cricket16WebRtcVideoFrame4InitEjiiiiPhmmmlli
+   fun:_ZN14VideoFrameTestIN7cricket16WebRtcVideoFrameEE19ConstructI4201PixelEv
+   fun:_ZN45WebRtcVideoFrameTest_ConstructI4201Pixel_Test8TestBodyEv
+}
+{
+   bug_3789_2
+   Memcheck:Uninitialized
+   fun:_ZN7cricket10VideoFrame8ValidateEjiiPKhm
+   fun:_ZN14VideoFrameTestIN7cricket16WebRtcVideoFrameEE13ValidateFrameEPKcjiib
+   fun:_ZN14VideoFrameTestIN7cricket16WebRtcVideoFrameEE21ValidateI420LargeSizeEv
+   fun:_ZN47WebRtcVideoFrameTest_ValidateI420LargeSize_Test8TestBodyEv
+}
+{
+   bug_3789_3
+   Memcheck:Uninitialized
+   fun:_ZN7cricket10VideoFrame8ValidateEjiiPKhm
+   fun:_ZN7cricket16WebRtcVideoFrame5ResetEjiiiiPhmmmlli
+   fun:_ZN7cricket16WebRtcVideoFrame4InitEjiiiiPhmmmlli
+   fun:_ZN14VideoFrameTestIN7cricket16WebRtcVideoFrameEE18CopyToBuffer1PixelEv
+   fun:_ZN44WebRtcVideoFrameTest_CopyToBuffer1Pixel_Test8TestBodyEv
+}
+{
+   bug_3789_4
+   Memcheck:Uninitialized
+   fun:_ZN7cricket10VideoFrame8ValidateEjiiPKhm
+   fun:_ZN7cricket16WebRtcVideoFrame5ResetEjiiiiPhmmmlli
+   fun:_ZN7cricket16WebRtcVideoFrame4InitEPKNS_13CapturedFrameEii
+   fun:_ZN20WebRtcVideoFrameTest8TestInitEii
+   fun:_ZN38WebRtcVideoFrameTest_InitEvenSize_Test8TestBodyEv
+}
+{
+   bug_3789_5
+   Memcheck:Uninitialized
+   fun:bcmp
+   fun:_ZN7cricket10VideoFrame8ValidateEjiiPKhm
+   fun:_ZN14VideoFrameTestIN7cricket16WebRtcVideoFrameEE13ValidateFrameEPKcjiib
+   fun:_ZN14VideoFrameTestIN7cricket16WebRtcVideoFrameEE21ValidateI420LargeSizeEv
+   fun:_ZN47WebRtcVideoFrameTest_ValidateI420LargeSize_Test8TestBodyEv
+}
+{
+   bug_3789_6
+   Memcheck:Uninitialized
+   fun:bcmp
+   fun:_ZN7cricket10VideoFrame8ValidateEjiiPKhm
+   fun:_ZN7cricket16WebRtcVideoFrame5ResetEjiiiiPhmmmlli
+   fun:_ZN7cricket16WebRtcVideoFrame4InitEjiiiiPhmmmlli
+   fun:_ZN14VideoFrameTestIN7cricket16WebRtcVideoFrameEE19ConstructI4201PixelEv
+   fun:_ZN45WebRtcVideoFrameTest_ConstructI4201Pixel_Test8TestBodyEv
+}
+{
+   bug_3789_7
+   Memcheck:Uninitialized
+   fun:bcmp
+   fun:_ZN7cricket10VideoFrame8ValidateEjiiPKhm
+   fun:_ZN7cricket16WebRtcVideoFrame5ResetEjiiiiPhmmmlli
+   fun:_ZN7cricket16WebRtcVideoFrame4InitEPKNS_13CapturedFrameEii
+   fun:_ZN20WebRtcVideoFrameTest8TestInitEii
+   fun:_ZN38WebRtcVideoFrameTest_InitEvenSize_Test8TestBodyEv
+}